ReAct - Action on Antibiotic Resistance

ReAct is an independent network dedicated to the problem of antibiotic resistance. ReAct is a global catalyst, advocating and stimulating for global engagement on antibiotic resistance through a broad range of collaborations.


New meeting report - A planetary threat but a financing orphan

How should needed work on antimicrobial resistance be funded? New meeting report from workshop with experts on antimicrobial resistance and global health. The report includes strong evidence from a number of low- and -middle income countries about the extreme difficulty in identifying funds for priority activities and human resources. There is currently no ‘go-to-place’ for funding the implementation of National Action Plans on AMR and this is a serious concern.The report is prepared by ReAct and the Dag Hammarskjöld Foundation. Read full report: A planetary threat but a financing orphan.


How should urgently needed work on antimicrobial resistance be funded? Meeting report from workshop with experts on AMR and global health

It is widely acknowledged that the consequences of antimicrobial resistance will negatively affect and potentially jeopardize the progress and achievement of sustainable development. In December 2018, ReAct and the Dag Hammarskjöld Foundation hosted a meeting in Uppsala, Sweden, inviting around 20 experts in the field of antimicrobial resistance and global health, to discuss funding for the global crisis of antimicrobial resistance.


Sustainable investments in solutions to address antibiotic resistance

Investing to deliver on the objectives of the Global Action Plan on Antimicrobial Resistance is urgently needed. The return of economic and health investments in managing antimicrobial resistance will be large and are needed across several sectors to minimize the negative impact of antimicrobial resistance.

ReAct Interview

Peter Yeboah - from rural Ghana to representing 41 organizations in 30 countries - engaging in antibiotic resistance

Peter Yeboah, Chairman and Executive Director, is an optimist. He thinks recent experiences with epidemic outbreaks in Africa demonstrate that global health security lies in strengthening sub-Saharan African health systems.


What is appropriate, rational and prudent antibiotic use?

Appropriate, rational or prudent use of antibiotics are widely used terms when discussing the causes of and remedies for antibiotic resistance. Much like the term One Health, appropriateness of antibiotic use is intuitively appealing – its meaning seems obvious and most people would say that one should not use antibiotics inappropriately. But still we see a lot of misuse of antibiotics all over the world, so either there are many people who simply do not care about appropriate use of antibiotics, or perhaps the meaning is not so obvious as it first seems.


Innovate4AMR: Meet the eleven winning teams and their innovative projects

Innovate4AMR is a global online competition inviting student teams from around the world to design innovative solutions for antimicrobial stewardship in resource-limited healthcare settings. Meet the winning teams from Peru, India, Uganda, Honduras, Nigeria, Canada, the Philippines, the USA and China and learn about their innovative projects.


Combating antimicrobial resistance in Africa to achieve the 2030 Agenda

Beginning November ReAct Africa hosted its 3rd annual conference. This regional conference brought together 67 participants from 22 African countries. A truly One Health representation, the conference had almost equal representation from the human health, animal health, agriculture and environment sectors. Read about takeaways from the conference.


ReAct highlights during World Antibiotic Awareness Week 2018

During World Antibiotic Awareness Week, ReAct Africa, ReAct Asia Pacific and ReActLatin America arranged about 40 activities to raise awareness and to change behavior in Kenya, Uganda, Malawi, Zimbabwe, Nigeria, Sierra Leone, Indonesia, Thailand, India, Ecuador and Argentina. We also published a few articles. Learn more about the ReAct WAAW highlights.


Four take-aways from the WHO consumption report

On the first day of the World Antibiotic Awareness Week, WHO released the first global surveillance report on antimicrobial consumption. Read article, where we present four take-aways from the report to provide some overview and help with reading and interpreting the report.


Animal drug companies fuelling antibiotic resistance

A steady rise in per capita income, growing urban population and falling retail prices of chicken meat have made poultry production one of the fastest growing segments of the agricultural sector in India today. As a result, India is now the world’s fifth largest egg producer and the eighteenth largest producer of broilers. All this rapid expansion has however come at a high cost. The indiscriminate use of antibiotics, for growth promotion in particular in other words to ‘fatten chicken’, is fueling antibiotic resistance in the country.


UNCTAD and WHO focus in on investments for development of new antibiotics

During the World Investment Forum 2018, UNCTAD and WHO jointly organized an event on ‘Fostering investments in the development of new antibacterial treatments.

The event focused on promoting partnerships between funders and developers, where efforts and attention should be focused in the R&D process and how actors such as UNCTAD can bring relevant actors together to devise solutions to the current challenges in antibiotic discovery, research and development.


Increasing burden of antibiotic resistant infections - new data that require action

A new study in The Lancet Infectious Diseases reports an increase in the burden of antibiotic resistant infections in the EU/EEA. Now 33000 people die annually from antibiotic resistant bacterial infections, an increase from 10 years ago. In Europe, the burden is actually comparable to that from HIV, TB and influenza combined.


What’s cooking in the antibiotic pipeline?

For years, ReAct has talked about the discovery void: the fact that no truly new antibiotics have been discovered and reached the market since the 1980’s. Unfortunately, this still holds true for non-TB antibiotics, although there may be some hope to be found in the most recent pipeline analyses.

In focus

7 ways penicillin has cured the world for 90 years

As we celebrate the 90th anniversary of the discovery of penicillin, it is appropriate to take a look at the current state of modern medicine since the discovery penicillin and the other antibiotics that followed. Here are seven ways that penicillin changed modern medicine.


One Health – working together for improved antibiotic use

One Health is often used as a buzzword – a word that evokes reactions and feels intuitively positive. Unfortunately, it is often poorly defined and understood. One attempt to define it is as a connectivity. The health of humans is connected to the health of animals and plants and vice versa. We all share this space, whether we call it a biome, ecosystem or Mother Earth.


Mass administration of antibiotics does not solve the root cause of child mortality in Africa

The situation for many children in sub-Saharan Africa is dire: a variety of infectious diseases, malnutrition and inadequate water, sanitation and hygiene infrastructure all take their toll in these most vulnerable. According to UNICEF, the estimated mortality rate in children under 5 years in sub-Saharan Africa in 2016 was 78.4 deaths per 1000 live births. We all share a responsibility to reduce these mortality rates, but how?


Rise in global antibiotic consumption between 2000 and 2015 – what can we learn from the latest study?

According to a recent publication in the Proceedings of the National Academy of Science, global antibiotic consumption in humans has increased dramatically from 2000 to 2015. The study rings a bell on the complex challenges posed by underuse, misuse and overuse of antibiotics.



Towards stronger global governance for AMR

As global attention and political will to address the rising tide of antibiotic resistance has increased over the last years, and a wider range of actors starting to become involved in the field, the urgency of developing global governance of antimicrobial resistance (AMR) is growing.

ReAct Story

Caring about antibiotic resistance is similar to reducing plastic waste or saving water

“Caring about antibiotic resistance is similar to reducing plastic waste or saving water”, says Dr. Windhi Kresnawati. She is a pediatrician and has worked in a remote area in Papua Island in Indonesia for the past 4 years. During this time she managed to engage various stakeholders to support and participate in a series of activities to raise their awareness on antibiotic resistance.



The rise and fall of antibiotics?

As we recently commemorated the World Health Day, it is interesting to remind us all of the rise and approaching fall of one of the most powerful discoveries in medical history – antibiotics. What makes them so special, and why is bacterial resistance such a major threat to human health?


The ethics of antibiotic resistance

Bacterial resistance to antibiotics gives rise to new ethical problems. Much of medical ethics prior to antibiotics has been focused on whether a certain procedure is justified, for example with respect to safety, efficacy and costs. But as antibiotic resistance has a global impact that persists over time, new questions arise that cannot be solved only by more or better science. In contrast with science, which is descriptive, ethics is normative. Ethics deals with what we ought to do or ought not to do.


Antibiotic resistance strikes hardest at the poor

It is a well-known fact that antibiotic resistant infections have a major influence on the health of people globally. Antibiotic resistance increases both mortality and morbidity due to treatment failures and lack of effective therapy. But antibiotic resistance has even more far-reaching consequences on different levels that often tend to be overlooked.

The ReAct Toolbox

The ReAct Toolbox is a user-friendly web-based resource that provides inspiration and guidance to take action and develop national action plans on antibiotic resistance. It is built on what has been done in the past in a variety of settings, and is aligned with ongoing and current initiatives from across the globe.

We are global

ReAct is a global network of antibiotic resistance experts with nodes in Africa, Asia Pacific, Europe, Latin America and North America.

Antibiotic resistance

In the last 70 years the use of antibiotics has been crucial in improving countless lives and drastically reducing deaths caused by bacterial infections. The increasing development of antibiotic resistance is posing a serious threat to human health and development, the environment and for animal health. Learn more about ReAct’s work on antibiotic resistance here.

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National Action Plans

Involved in developing your country's National Action Plan? Here you find support for developing a comprehensive plan.

Health Care Professionals

Doctors, pharmacists, veterinarians and other health care professionals - you have the power to take action! Learn more about how to get started.

Civil Society Organizations

Engagement from civil society organizations and communities is needed to tackle antibiotic resistance. Learn more about how to get involved.