The COVID-19 pandemic has led to an increased interest among news outlets and the public in the advancement of clinical trials. Results from studies are sometimes presented as headline news, but unfortunately often with little reflection or critical analysis. Here we try to explain some of the basic concepts and terms, and reflect on how study design affects what conclusions can be drawn from the studies.
ReAct is an independent network dedicated to the problem of antibiotic resistance. ReAct is a global catalyst, advocating and stimulating for global engagement on antibiotic resistance through a broad range of collaborations.
Articles relating to COVID-19 and antibiotic resistance.
The WHO GLASS-report summarizing antimicrobial resistance data from 2018 was launched end of May this year. The report is built on data reported from 78 of the 82 countries that were enrolled in GLASS at the end of the data call – 31st of July 2019 – and includes information extracted from over two million infected patients. In this article, ReAct highlights important findings in the report, describes the progress of GLASS and points out pitfalls to be aware of when interpreting the data.
Earlier this week, ReAct provided feedback on the establishment of an Independent Panel on Evidence for Action against Antimicrobial Resistance. Also, the Antibiotic Resistance Coalition came together around a joint response on the proposed Terms of Reference that the Tripartite Joint Secretariat on AMR had issued a public discussion on.
Being a zoologist, Jessica Mitchell worked in different countries traveling to remote sites and engaged with the local communities. She enjoyed being able to bring her biological knowledge to an applied problem and support communities to develop their own solutions.
This is when she realized she wanted to develop her human behavior skillset and at the same time use her biology background to address applied problems – such as antimicrobial resistance.
A key component of delivering new antibiotics to market is ensuring that they are used appropriately. To learn how this can be done, ReAct looked into how bedaquiline, a new anti-tuberculosis drug was introduced in South Africa. A key learning point from the project was that the requirements for sustainable use of antibiotics correlate with the building blocks of a strong health system – health systems strengthening and responsible use of antibiotics go hand in hand.
Shortages of antibiotics have become a global problem that also affect countries with robust healthcare and regulatory systems. The causes are several, sometimes difficult to oversee, and the solutions are not as easy to implement as they are to conceptualize. Shortages of medicines in general cause patients to lose access to important treatments and, as such, lead to increased costs, morbidity and even mortality. But shortages of antibiotics may also lead to increases in antibiotic resistance.
Here you find links to articles, reports and short videos – to learn more about the impact of Antimicrobial Resistance on Universal Health Coverage, the Sustainable Development Goals and the urgent need to find ways to finance efforts to manage antimicrobial resistance.
The ReAct Toolbox is a user-friendly web-based resource that provides inspiration and guidance to take action and develop national action plans on antibiotic resistance. It is built on what has been done in the past in a variety of settings, and is aligned with ongoing and current initiatives from across the globe.
ReAct is a global network of antibiotic resistance experts with nodes in Africa, Asia Pacific, Europe, Latin America and North America.
In the last 70 years the use of antibiotics has been crucial in improving countless lives and drastically reducing deaths caused by bacterial infections. The increasing development of antibiotic resistance is posing a serious threat to human health and development, the environment and for animal health. Learn more about ReAct’s work on antibiotic resistance here.
Involved in developing your country's National Action Plan? Here you find support for developing a comprehensive plan.
Doctors, pharmacists, veterinarians and other health care professionals - you have the power to take action! Learn more about how to get started.
Engagement from civil society organizations and communities is needed to tackle antibiotic resistance. Learn more about how to get involved.