Knowledge about antibiotic resistance levels in bacteria from both humans and animals and how common these bacteria are, is key to guide appropriate treatment of patients and animals, as well as for understanding the scale of the problem and address it appropriately.
Please note that it is useful to examine resistance in both humans and animals in parallel, to track resistance trends and detect for example emerging resistance or outbreaks. The table below collects resources with a cross-sectorial, or ‘One Health’ perspective. Also, several reports present data from both humans and animals, and may therefore be found on all sub-pages.
The Antimicrobial Resistance Centre – a research platform for AMR
The Antimicrobial Resistance Centre, hosted by the London School of Hygiene and Tropical Medicine, is a research hub gathering researchers from a multitude of disciplines. Research projects are currently ongoing in 30 countries. The overall aim of the work conducted at the centre is to describe where, how and why antimicrobial resistance (AMR) is a problem and to develop, model, evaluate and translate innovative solutions. The research is divided into five pillars: biological and pharmacological sciences, clinical and veterinary sciences, economic, social and political sciences, epidemiology and modelling and humanities and environmental sciences. The Antimicrobial Resistance Centre frequently hosts webinars and other events, and is providing fortnightly newsletters about AMR research, news, events and funding.
While the Toolbox contains some references to scientific papers, there is a large quantity of studies of varying quality published in the scientific literature. Search for example for “antibiotics AND [your country]” in one of the the databases below:
|Integrated surveillance of antimicrobial resistance in foodborne bacteria: Application of a One Health approach||Guide designed for WHO Member States and other stakeholders for designing an integrated surveillance program using standardized and validated antimicrobial susceptibility testing methods and harmonized interpretative criteria. Read more about the WHO Advisory Group on Integrated Surveillance of Antimicrobial Resistance (AGISAR) here|
|ECDC, EFSA and EMA Joint Scientific Opinion on a list of outcome indicators as regards surveillance of antimicrobial resistance and antimicrobial consumption in humans and food-producing animals||Indicators: Suggestion of outcome indicators with a ‘One Health’ perspective for monitoring progress of surveillance of antimicrobial resistance and antimicrobial consumption in humans and food-producing animals, with methodology for how indicators were selected, and examples of calculation of indicators. Established by European health and food safety agencies.|
|ECDC/EFSA/EMA joint reports on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals (JIACRA reports)||Report. Using existing data from Europe, ECDC/EFSA/EMA analyze the relationship between antimicrobial consumption and resistance to the same antimicrobials in bacteria from humans and animals.|
|A conceptual framework for the environmental surveillance of antibiotics and antibiotic resistance||Journal article proposing a framework for how to use environmental samples for surveillance of antibiotic consumption and antibiotic resistance. The framework contains five objectives of surveillance together with proposed markers and sampling sites.|