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Measure  –  Appropriate use

Food animals

This section provides information and resources to measure prudent use of antibiotics in food animals. You can also access selected data sources and relevant reports.

In the food animal sector, the preferred term for appropriate use is responsible and prudent use. Antibiotics are used to treat diseases, to prevent and control diseases and, in parts of the world, to promote animal growth. Thus, part of the antibiotic use is for non-therapeutic purposes. Inappropriate or imprudent use of antibiotics increases the risk of development of antibiotic resistance in bacteria, which in turn can lead to therapy failure, bringing negative consequences for animal welfare as well as economic losses

FAO/WHO and OIE have developed guidelines that outline the responsibilities of different actors related to responsible and prudent use. Actors include competent authorities, pharmaceutical industry, distributors, veterinarians and food animal producers.

Evaluations on appropriateness of antibiotic use in the animal sector may address the following:

  • Record keeping of antibiotic use at both farm level and individual veterinary level
  • Antibiotic use as growth promotors
  • Other non-therapeutic use, such as routine prevention during certain risk-periods (e.g. weaning of piglets)
  • Use of critically important antibiotics and under which indication
  • Are antibiotics prescribed by a veterinarian?

The resources below have been divided into the following tables:

  • Tools and guidelines
  • Data and reports

See also related sections on Consumption and Knowledge and practices.

Selected Resources

Tools and guidelines

Resource Description
Keeping veterinary medicine records Guidance on how to keep veterinary medicine records. Includes an example format on record keeping (word document). Guidance for England, but can be used for inspiration/adapted for other contexts.
OIE Terrestrial Animal Health Code Chapter 6.10: Responsible and prudent use of antimicrobial agents in veterinary medicine.
The Veterinary Benchmark Indicator (VBI) Methodology from the Netherlands Veterinary Medicines Institute (SDa) on benchmarking usage of antibiotics on farms. The benchmarking classifies farms and veterinarians into “target, “signaling” and “action” zones. This page contains the original report (PDF,  0.8 MB) on the benchmarking and a report with revisions made to it (PDF, 2.2 MB). The annual reports contain the latest updates to the benchmarking thresholds.

Data and reports

Resources Description
Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis Systematic review on the effect of interventions restricting antibiotic use in food animal production. Provides evidence that restricting use lowered the presence of antibiotic resistant bacteria in the animals. The appendix lists all studies (2MB) included in the review and provides a quality assessment.
Reduction of Veterinary Antimicrobial Use in the Netherlands. The Dutch Success Model Journal article that describes and analyses the processes and actions behind the transition from abundant antimicrobial use in farm animals in the Netherlands towards a more prudent application of antimicrobials.
Effects of Banning the Use of Antibiotics as Growth Promoters in Denmark and Scandinavi (PDF) Reference collection. Document with links to major reports and journal articles describing the experiences in the Scandinavian countries of banning the use of antibiotics as growth promoters. See also fact sheet on Danish experience (The PEW Charitable Trusts).
Restrictions on antimicrobial use in food animal production: an international regulatory and economic survey Journal article comparing governmental policies on antimicrobial use in food animal production, showing that antibiotic use differs widely, from no restrictions to strict restrictions.

More from "Appropriate use"

1.
World Health Organization - WHO. Critically Important Antimicrobials for Human Medicine [Internet]. WHO. [cited 2019 Jun 4]. Available from: http://www.who.int/foodsafety/areas_work/antimicrobial-resistance/cia/en/
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Autoriteit Diergeneesmiddelen. The Veterinary Benchmark Indicator (VBI) [Internet]. 2014 [cited 2016 May 10]. Available from: http://www.autoriteitdiergeneesmiddelen.nl/en/publications
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Hampshire County Council. Keeping veterinary medicine records [Internet]. Hantsweb. [cited 2016 Jul 5]. Available from: https://www.hants.gov.uk/business/tradingstandards/businessadvice/animalhealth/veterinarymedicine
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Tang KL, Caffrey NP, Nóbrega DB, Cork SC, Ronksley PE, Barkema HW, et al. Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis. The Lancet Planetary Health [Internet]. 2017 Nov 1;1(8):e316–27. Available from: http://www.sciencedirect.com/science/article/pii/S2542519617301419
1.
World Organisation for Animal Health - OIE, editor. Terrestrial Animal Health Code [Internet]. 24th ed. Paris: OIE; 2015. 411 p. (Terrestrial animal health code; vol. 1). Available from: http://www.oie.int/en/international-standard-setting/terrestrial-code/access-online/
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Maron DF, Smith TJS, Nachman KE. Restrictions on antimicrobial use in food animal production: an international regulatory and economic survey. Global Health [Internet]. 2013;9:48. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24131666
1.
The PEW Charitable Trusts. Effects of Banning Antibiotics as Growth Promoters in Denmark, Scandinavia [Internet]. Research and analysis. 2010 [cited 2016 Apr 5]. Available from: http://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2010/07/27/effects-of-banning-the-use-of-antibiotics-as-growth-promoters-in-denmark-and-scandinavia
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Bengtsson B, Greko C. Antibiotic resistance—consequences for animal health, welfare, and food production. Upsala Journal of Medical Sciences [Internet]. 2014 [cited 2016 Apr 5];119(2):96–102. Available from: http://www.tandfonline.com/doi/full/10.3109/03009734.2014.901445
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Speksnijder DC, Mevius DJ, Bruschke CJM, Wagenaar JA. Reduction of Veterinary Antimicrobial Use in the Netherlands. The Dutch Success Model. Zoonoses Public Health [Internet]. 2014 Nov 25; Available from: http://www.ncbi.nlm.nih.gov/pubmed/25421382
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Centers for Disease Control and Prevention - CDC. Core Elements - Implementation Resources - Get Smart for Healthcare [Internet]. [cited 2015 Apr 23]. Available from: http://www.cdc.gov/getsmart/healthcare/implementation/core-elements.html