News & Views

Publications

Share the article

Publications by ReAct or co-authored by ReAct

J. of Law, Medi & Ethics

Equitable access to antibiotics: A core element for pandemic preparedness and response

In an article published in the latest Symposium Issue of the Journal of Law, Medicine & Ethics “Antimicrobial Resistance Must Be Included in the Pandemic Instrument to Ensure Future Global Pandemic Readiness”, ReAct calls for securing equitable and sustainable access to effective antibiotics and other countermeasures to be a key consideration in the upcoming pandemic instrument.

Lancet Global Health

Lancet article: Transferable exclusivity voucher: A flawed incentive to stimulate antibiotic innovation

In February 2023 a new article was published in The Lancet co-authored by ReAct Europe’s Otto Cars and Kerstin Åkerfeldt called “Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation”.

The article argues why the proposed transferable exclusivity voucher (TEV), which has been suggested by the European Commission as a potential new incentive to be introduced in the revision of the EUs pharmaceutical legislation to stimulate antibiotic innovation should be abandoned.

UNEP report

Bracing for Superbugs: Strengthening environmental action in the One Health response to antimicrobial resistance

The United Nations Environment Programme (UNEP) recently released a new report on the environmental dimensions of antimicrobial resistance (AMR) highlighting how the misuse and overuse of antibiotics in humans, animals, and agriculture can contribute to the spread of drug-resistant infections. This, in turn, can cause severe consequences for public health, food security, and ecosystems.

Anthony So, Director of the ReAct Strategic Policy Program and the IDEA (Innovation + Design Enabling Access) Initiative at Johns Hopkins Bloomberg School of Public Health, is one of five lead authors of the report.

Lancet Global Health

An analysis of existing national action plans for antimicrobial resistance—gaps and opportunities in strategies optimising antibiotic use in human populations

The Lancet article titled “An analysis of existing national action plans for antimicrobial resistance – gaps and opportunities in strategies optimising antibiotic use in human populations” examines the existing National Action Plans on Antimicrobial Resistance and identifies gaps and opportunities for improving strategies to optimize antibiotic use in human populations. Dr. Mirfin Mpundu, ReAct Africa, contributed to the article as one of the co-authors.

Lancet Global Health

Resetting the agenda for antibiotic resistance through a health systems perspective

Resetting the agenda for antibiotic resistance through a health systems perspective

JOURNAL ARTICLE

Antibiotic and pesticide susceptibility and the Anthropocene operating space

Antibiotic and pesticide susceptibility and the Anthropocene operating space (Nov 2018).

JOURNAL ARTICLE

Multidisciplinary and multisectoral coalitions as catalysts for action against antimicrobial resistance: Implementation experiences at national and regional levels

Multidisciplinary and multisectoral coalitions as catalysts for action against antimicrobial resistance: Implementation experiences at national and regional levels (March 2018).

JOURNAL ARTICLE

Unavailability of old antibiotics threatens effective treatment for common bacterial infections

Unavailability of old antibiotics threatens effective treatment for common bacterial infections (March 2018).

Journal article

Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia

This paper co-authored by ReAct and points out old but clinically useful antibiotics are not available in all countries. The situation regarding availability of these ‘forgotten antibiotics’ has worsened since 2011.

Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia (Jan 2017).

Journal article

Use antimicrobials wisely

In this article, authors argue that UN must reframe action on antimicrobial resistance as the defence of a common resource. Better understanding can facilitate action on AMR from varying angles, namely infectious diseases, food security, natural resources and environmental conservation.
Use antimicrobials wisely (Sept 2016).

Journal article

A Global Antimicrobial Conservation Fund for Low- and Middle-Income Countries

This paper co-authored by ReAct points out to the critical need to scale-up funding for low- and middle-income countries to support antimicrobial conservation and proposes a formation of the fund coordinating such support.
A Global Antimicrobial Conservation Fund for Low- and Middle-Income Countries (Oct 2016).

Journal article

Antimicrobial resistance - a threat to the world's sustainable development

This paper examines how a number of the Sustainable Development Goals (SDGs) are impacted by antimicrobial resistance and suggests how to integrate the issue better into ongoing international policy processes using SDGs as an entry point.
Antimicrobial resistance-a threat to the world’s sustainable development (Aug 2016).

Journal article

UN High-Level Meeting on antimicrobials – what do we need?

In the light of culminating political attention to AMR at the 71st UN General Assembly, this paper highlights four key functions the ad hoc global coordinating mechanisms should bear, namely advocacy, monitoring and evaluation, resource mobilisation and coordination of multisectoral action.
UN High-Level Meeting on antimicrobials–what do we need? (July 2016).

Journal article

Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming a Promising Idea into Reality

The paper discusses different aspects of the delinkage model, the most promising incentive mechanism proposed to replace the current business model for antibiotics. Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming Promising Idea into Reality (June 2016).

Journal article

Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance

The world has a collective responsibility to preserve antibiotic effectiveness and access for all. This paper lays down policy implications and global governance tools necessary to addressed to resolve access vs. excess dilemma.
Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance (Aug 2015).

Journal article

An international legal framework to address antimicrobial resistance

Authors propose a concept of a tripod – access, conservation, innovation – where all of these three areas need to be addressed simultaneously to maintain sustainability in global action. The paper also explores tools of an international law that can be utilised in assuring countries’ commitment to act.
An international legal framework to address antimicrobial resistance (Feb 2015).

Journal article

International cooperation to improve access to and sustain effectiveness of antimicrobials

In this paper, authors elucidates interlinkages between access, conservation and innovation of antibiotics and the need to address these three elements simultaneously. Because of the multisectoral nature of the problem, having key global institutions and partners aligned under a One Health model is necessary.
International cooperation to improve access to and sustain effectiveness of antimicrobials (Jan 2016).

Journal article

An Integrated Systems Approach is Needed to Ensure the Sustainability of Antibiotic Effectiveness for Both Humans and Animals

This paper identifies issues related to the use of antimicrobials in food-producing animals, provides examples of regional and country-level policies regulating non-therapeutic use of antibiotics and emphasises the need for a global coordination via international agreement to address these issues.
An Integrated Systems Approach is Needed to Ensure the Sustainability of Antibiotic Effectiveness for Both Humans and Animals (Aug 2015).

Journal article

Overcoming scientific and structural bottlenecks in antibacterial discovery and development

Both financial and scientific bottlenecks hinder R&D of novel antibiotics. This paper delve deeper into the specifics of the different scientific and structural barriers, and offers some potential solutions.
Overcoming scientific and structural bottlenecks in antibacterial discovery and development (May 2014).

Journal article

Antibiotic resistance-the need for global solutions

This article series describes the global situation of antibiotic resistance, its major causes and consequences. Authors identify key areas spanning from epidemiology to global governance in which action is urgently needed.
Antibiotic resistance-the need for global solutions (Dec 2013).

Journal article

3Rs for innovating novel antibiotics: sharing resources, risks, and rewards

This article examines bottlenecks in the antibiotic pipeline. Authors argue that effective solutions are likely to include sharing the three Rs—resources, risks, and rewards along antibiotic development from discovery to post-marketing phases.
3Rs for innovating novel antibiotics: sharing resources, risks, and rewards (2012).