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ReAct Interview

Nurse Dorce, Indonesia: Treating small patients with much love and infection prevention - a success story

Nurse Dorce Datu, head of the Neonatal Intensive Care Unit at Biak Hospital, Indonesia, has been working in the unit since the first day it was founded. She has seen the days when the death rate of premature babies with infection was 100%, and now she is the one who keeps the Infection Prevention Control Program at the unit running.

Her main goal is to create a supportive environment for the staff and she is not afraid of going the extra mile to help them and their small patients. She is a nurse who – together with the unit and the hospital – acts conscientiously on antibiotic resistance. We need more nursing professionals like Nurse Dorce and her team.

News

Children at Risk: New ReAct film and global survey – ReAct’s asks of leaders!

Life-threatening infections in children are becoming untreatable. ReAct releases a short film and a global survey to get the attention from leaders in governments, from donors and from professional societies and civil society. The film portrays how children’s lives are at risk due to the threat of antibiotic resistance. The message from the survey is clear – physicians across the globe are worried about losing the very drugs that can save these children’s lives. Leaders need to act now. See ReAct’s asks of governments, donors, professional societies, and civil society.

Theme

COVID-19 and antibiotic resistance

ReAct articles relating to COVID-19 and antibiotic resistance.

News

New ReAct film: Children at risk - The threat of antibiotic resistance

This ReAct film, directed by Staffan Hildebrand, depicts how effective antibiotics are crucial for the survival of children with severe bacterial infections – all over the globe. The short film shows the reality – how children’s lives are at risk due to the threat of antibiotic resistance.

News

ReAct highlights during World Antimicrobial Awareness week 2020

Online activity will mark World Antimicrobial Awareness Week in 2020. This to help address the current pandemic of Covid-19 – and – at the same time – put focus on the silent pandemic of antimicrobial resistance. Still, ReAct leaves this year’s World Antimicrobial Awareness Week behind with a smile on its face. A week of interaction and intensified work on antimicrobial resistance is really motivating and strengthening – for a world free from untreatable infections.

Policy

ReAct Open Letter: 5 key points to One Health Global Leaders Group on Antimicrobial Resistance

Today, the One Health Global Leaders Group on Antimicrobial Resistance was announced by the United Nations Tripartite organizations World Health Organization, UN Food and Agriculture Organization, and the International Organization on Animal Health. ReAct has written an open letter to the Group’s co-chairs their Excellencies, Sheikh Hasina, Prime Minister of Bangladesh and Mia Mottley, Prime Minister of Barbados.

News

New ReAct Report: Treatment of newborn sepsis is threatened – effective antibiotics essential

Neonatal sepsis, a condition caused by the body’s response to infections, affects four million newborns globally every year. It makes up 15% of all neonatal deaths and the majority occur in low-income countries. Alarmingly, and further complicating an already lethal condition, up to 40% of neonatal sepsis cases are due to resistant pathogens. Today, on World Children’s Day, ReAct releases a new report on newborns, sepsis and antibiotic resistance.

ReAct Interview

My patients can recieve 5-10 courses of antibiotics during their cancer treatment

Dr. Honar Cherif has worked as a doctor for 29 years in Sweden at Karolinska Institutet and Uppsala University Hospital.

He says: “A worrying development has been reported in many European countries for some years now. Infections caused by multi-resistant bacteria such as MRSA and ESBL do not respond to the broad-spectrum antibiotics we use to manage infections in these immunocompromised patients.”

Science and policy

New ReAct Report: antibiotic resistance affects men and women differently

Sex and gender is important to consider in enhancing the understanding of the ‘human face’ of antibiotic resistance and antibiotic use, and how it affects a variety of people in different ways throughout their daily lives. ReAct now issues a report that explores the ways in which sex and gender interact with antibiotic resistance and makes the case for all actors engaged in addressing antibiotic resistance to undertake further work in this area.

Science and policy

4 take aways from WHO’s first global report on sepsis

In September, the WHO released their first Global Report on the Epidemiology and Burden of Sepsis.

The report draws attention to:
– the threat of resistant infections to sepsis patients
– the opportunities that exist in integrating our surveillance and response to antibiotic resistance.

Here ReAct highlights four take aways in the shared challenges – and point out tools that unite the global effort against sepsis and antibiotic resistance.

News

ReAct Asia Pacific: Photo competition for students - health in focus

ReAct Asia Pacific has been organizing photography competitions for students every year to commemorate the World Antimicrobial Awareness Week. Three editions of the competition has been organized so far, with a large number of entries coming from South and South East Asian countries. The primary objective of the competition has been to introduce the issue of antibiotic resistance to students and engage their creative energies.

Policy

The new Pharmaceutical Strategy for Europe – an opportunity to put public interest first

ReAct welcomes the European Commission’s initiative to develop a new strategy for the pharmaceutical sector in Europe. The proposed strategy should be seen against the background of several years of heated discussions in Brussels on how to address the increasing problem of high-priced medicines and patients’ lack of access to such medicines in a number of EU Member States.

News

Launch of global student design sprint – Innovate4Health

ReAct North America (Strategic Policy Program) and the International Federation of Medical Students (IFMSA) are calling on students to take up the challenge and become the future innovators to address health inequities that are exacerbated by emerging infectious diseases, like drug-resistant infections and COVID-19.

Science

World Sepsis Day – antibiotics essential in treatment of sepsis

World Sepsis Day is coming up on September 13th. The day was initiated by the Global Sepsis Alliance in 2012 and aims to raise global awareness about sepsis, which every year causes many millions of deaths around the world. Bacterial infection is commonly the root cause of the condition, and prompt treatment with effective antibiotics is then essential for survival.

News

Key points from ReAct’s comments to the Independent Panel on Evidence

Earlier this week, ReAct provided feedback on the establishment of an Independent Panel on Evidence for Action against Antimicrobial Resistance. Also, the Antibiotic Resistance Coalition came together around a joint response on the proposed Terms of Reference that the Tripartite Joint Secretariat on AMR had issued a public discussion on.

News

4 key reflections on the recently launched WHO GLASS-report

The WHO GLASS-report summarizing antimicrobial resistance data from 2018 was launched end of May this year. The report is built on data reported from 78 of the 82 countries that were enrolled in GLASS at the end of the data call – 31st of July 2019 – and includes information extracted from over two million infected patients. In this article, ReAct highlights important findings in the report, describes the progress of GLASS and points out pitfalls to be aware of when interpreting the data.

ReAct Interview

From zoologist to community engagement on AMR

Being a zoologist, Jessica Mitchell worked in different countries traveling to remote sites and engaged with the local communities. She enjoyed being able to bring her biological knowledge to an applied problem and support communities to develop their own solutions.

This is when she realized she wanted to develop her human behavior skillset and at the same time use her biology background to address applied problems – such as antimicrobial resistance.

Science

What everyone needs to know about clinical research

The COVID-19 pandemic has led to an increased interest among news outlets and the public in the advancement of clinical trials. Results from studies are sometimes presented as headline news, but unfortunately often with little reflection or critical analysis. Here we try to explain some of the basic concepts and terms, and reflect on how study design affects what conclusions can be drawn from the studies.

News

ReAct Africa expands

ReAct Africa has continued to expand in the region since its inception, engaging with AMR champions, governments, academia, CSOs including Faith-based Organizations in more than 33 countries.

Policy

New ReAct Policy Brief: Successful cancer treatment relies on effective antibiotics

Antibiotics are instrumental for patients undergoing chemotherapy and surgery, and have paved the way for modern cancer care. Cancer patients often need antibiotics multiple times during the course of cancer treatment, which is why antibiotic resistance is seriously threatening patient outcomes. In ReAct’s new policy brief, you will learn more about the links connecting effective antibiotics and cancer care, and why urgent action on antibiotic resistance therefore is needed.

Theme

COVID-19 and antibiotic resistance

ReAct articles relating to COVID-19 and antibiotic resistance.

Policy

COVID-19 resolution – a missed opportunity to address global pandemic response more broadly

Last week’s World health Assembly was an opportunity to set out more ambitious goals to build stronger systems to prevent future pandemics and fundamentally reshape the way drug development is financed for pandemics, neglected diseases and antibiotics that isn’t restricted by the current market-based model. Despite high-level participation by several Heads of State showing that global health is finally becoming a political top priority, the final resolution did not go far enough on these crucial points.

Science

Impact of COVID-19 on vaccine-preventable diseases and antibiotic resistance

One of the consequences of the COVID-19 pandemic is that vaccination efforts that help control other diseases may be put on hold. This may lead to increased strain on health systems, morbidity and mortality due to vaccine-preventable disease and increases in antibiotic resistance.

News

ReAct Africa and Africa CDC: COVID-19 webinars

Coronavirus disease 2019 (COVID-19) – a pandemic that has claimed hundred of thousands of lives across the globe and spread to numerous African countries has caused an unprecedented global health threat. During this pandemic, ReAct Africa has partnered with Africa CDC in organizing and facilitating webinars to raise awareness on COVID-19.

News

Antibiotic pollution: India scores a global first with effluent limits

Start 2020 the Indian Ministry of Environment, Forest and Climate Change announced stringent standards on concentrations of antibiotics found in the waste discharged by pharmaceutical factories into rivers and the surrounding environment. By doing so it became the first state regulator anywhere in the world to introduce such standards, meant to reduce chances of creating drug-resistant bacteria.

Science

COVID-19 and AMR – what do we know so far?

SARS-CoV-2 is a new coronavirus. The virus causes the COVID-19 pandemic which currently requires the full focus, commitment and support from all governments, international institutions and organizations, the healthcare workforce, the private sector, civil society and the general public.

Some attention has started to be given to the role of secondary infections as well as antibiotic resistance in patients with COVID-19.

Science

Learning from bedaquiline in South Africa – comprehensive health systems for new antibiotics

A key component of delivering new antibiotics to market is ensuring that they are used appropriately. To learn how this can be done, ReAct looked into how bedaquiline, a new anti-tuberculosis drug was introduced in South Africa. A key learning point from the project was that the requirements for sustainable use of antibiotics correlate with the building blocks of a strong health system.

ReAct Interview

ReAct Interview: How does antibiotics in food animal production end up in the environment?

Lucas Alonso, researcher at the University de la Plata in Argentina, headed an unpublished work for Latin America last year. Together with a group of researchers, he showed that antibiotics are found as pollutants in rivers and streams of the Cuenca del Plata, one of the largest drainage basins in the world. Here he replies to a few questions on the subject.

Science

Shortages and AMR – why should we care? 4 consequences of antibiotic shortages

Shortages of antibiotics have become a global problem that also affect countries with robust healthcare and regulatory systems. Shortages of medicines in general cause patients to lose access to important treatments and, as such, lead to increased costs, morbidity and even mortality. But shortages of antibiotics may also lead to increases in antibiotic resistance.

News

Key take aways from CSO workshop on AMR in Kenya

End February Africa CDC and ReAct Africa convened a workshop targeting civil society organizations in the African region. The main objective of the workshop was to build capacity on antimicrobial resistance advocacy for civil society organizations. Here are some key take aways from the workshop and actions for 2020.

News

New fact sheet: Effective antibiotics - essential for childrens' survival

Infectious diseases are the leading cause of death in children under the age of 5 years old. Many of these infections are likely caused by resistant bacteria. To shed further light on how antibiotic resistance affects children ReAct has produced a short fact sheet.

Policy

The 2020 AMR Benchmark Report – concerning findings with questionable framing

A new AMR Benchmark report was released during the World Economic Forum in Davos in January 2020. While this new AMR Benchmark uncovers some truly concerning facts on company behavior, these findings are often not framed in a way that makes their significance clear. This brief ReAct assessment tries to put these findings in context and comments on the AMR Benchmark’s approach. Is the glass half full or half empty?

News

4 key reflections from engaging hospitals in India for antibiotic stewardship

Next month experts will gather in Bangkok at a WHO-organized meeting – this to discuss the roll-out of WHO’s new toolkit on Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries. I context of this ReAct takes the opportunity to share its reflections from a ReAct-led stewardship project in rural secondary level hospitals in India.

World Cancer Day

World Cancer Day: Cancer patients rely on effective antibiotics

We all know someone who has suffered from cancer: a family member, a friend or a colleague. Maybe yourself? Less well-known is how fundamental effective antibiotics are during the course of cancer treatment. Cancer patients rely on antibiotics for prevention and treatment of infections. This is one of the most common complications of their illness. Antibiotic resistance may have detrimental effects on cancer treatment outcomes.

ReAct Interview

Teacher Gustavo Cedillo, Ecuador, teaches children about the bacterial world

Gustavo Cedillo is a teacher in Cuenca, Ecuador. He is one of the teachers in the region using ReAct Latin America’s school material Alforja Educativa – The Educational Saddlebag. The material educates children about the world of bacteria. Professor Cedillo has worked as a teacher for 37 years and he really likes using a holistic perspective in his classes.

Science

Our microbiome and noncommunicable diseases

What is the relationship between the bacteria in us and our health? And can these bacteria cause diseases that we think are noncommunicable? In 2017, ReAct published a factsheet on the human microbiome that brought up some of these connections, but today we know even more as research has moved forward.