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Publications by ReAct or co-authored by ReAct

Frontiers

Knowledge, attitudes, and practices regarding antimicrobial use and antimicrobial resistance among medical students and house surgeons in India: a call to reform medical curricula and training practices

The study concludes that Indian medical students and house surgeons have moderate knowledge and positive attitudes toward AMR, but important gaps in understanding and antimicrobial-use practices, compounded by limited formal AMR training. It calls for early integration of AMR education, rational prescribing, patient assessment and antimicrobial stewardship into the national medical curriculum.

Knowledge, attitudes, and practices regarding antimicrobial use and antimicrobial resistance among medical students and house surgeons in India: a call to reform medical curricula and training practices.

Community engagement

Bridging AMR knowledge gaps and improving policy implementation: a perspective on the role of community engagement in Africa

This perspective article suggests that community engagement has the potential to improve AMR outcomes by generating more community-relevant, context-specific AMR knowledge, providing novel data and evidence for action.

Bridging AMR knowledge gaps and improving policy implementation: a perspective on the role of community engagement in Africa.

Youth engagement

Youth as change makers on antimicrobial resistance: an evidence-based call-to-action

This commentary describes the co-creation process of the Youth Manifesto on AMR which seeks to generate consensus on how equitable engagement of youth can be realised, despite policy, power and funding challenges.

Youth as change makers on antimicrobial resistance: an evidence-based call-to-action.

Infect Prev in Practice

Antibiotic Resistance Profiles in Gram-negative Bacteria Causing Bloodstream and Urinary Tract Infections in Paediatric and Adult Patients in Ndola District, Zambia, 2020-2021

​The study provides critical insights into the prevalence and resistance patterns of Gram-negative bacteria (GNB) in two major hospitals in Ndola, Zambia.

Antibiotic Resistance Profiles in Gram-negative Bacteria Causing Bloodstream and Urinary Tract Infections in Paediatric and Adult Patients in Ndola District, Zambia, 2020 – 2021 (September 2025).

The Lancet

Integrating gender and equity commitments in the revised global action plan on antimicrobial resistance

The article highlights the importance of the revision of the Global Action Plan (2025 – 2026) on antimicrobial resistance. Calling for the integration of equity, gender, and social determinants into AMR priorities, ensuring a people-centred approach aligned with Global Health and Sustainable Development Goals (SDGs).

Integrating gender and equity commitments in the revised global action plan on antimicrobial resistance (September 2025).

The Lancet

The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics

Antimicrobial resistance (AMR) threatens the backbone of modern medicine and is already leading to deaths and disease which would have once been prevented. A series by The Lancet highlights AMR, the people most affected by AMR, how to rethink drug development moving forward, and much more.

The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics (May 2024).

The Lancet Reg Health

Community engagement to mitigate antimicrobial resistance in low-and middle-income countries – an essential strategy for implementation of national action plans on AMR

The article describes the vital role of a whole-of-society and one-health approach for prevention and mitigation of AMR. To ensure optimal policy implementation, community engagement should therefore be a priority for AMR action.

Community engagement to mitigate antimicrobial resistance in low-and middle-income countries – an essential strategy for implementation of national action plans on AMR (May 2024).

The Lancet global Health

Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance

The article highlights the urgent need to rebalance global efforts against antimicrobial resistance by prioritizing infection prevention interventions (ie, clean water and safe sanitation, increased vaccine coverage, and enhanced infection prevention measures for food production) in the Global South and aligning funding with regional needs to ensure an effective response.

Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance (March 2024).

BMC Public Health

Impact of the ´Alforja Educativa' on Ecuadorian schoolchildren's knowledge of bacteria, antibiotics, and antibiotic resistance, a pretest-posttest study

Educational initiatives are important as part of strategies to mitigate antibiotic resistance. The Alforja Educativa is an innovative educational program developed in Ecuador with the aim to teach schoolchildren about antibiotic use and antibiotic resistance. The article evaluates the effect of the Alforja Educativa on knowledge about bacteria, antibiotics and antibiotic resistance amongst fifth and sixth grade Ecuadorian schoolchildren.

Impact of the ´Alforja Educativa’ on Ecuadorian schoolchildren’s knowledge of bacteria, antibiotics, and antibiotic resistance, a pretest-posttest study (March 2024).

Infectious Diseases

The language of antimicrobial and antibiotic resistance is blocking global collective action

There are multiple gaps in the global and local responses to antibiotic resistance. One aspect causing this complacency is the language that is used to describe the problem and its consequences.This article surveys examples of the current discussions around antibiotic resistance and seek to offer a path towards a unified and understandable narrative.

The language of antimicrobial and antibiotic resistance is blocking global collective action (March 2024).

Antibiotics

Formulating a Community-Centric Indicator Framework to Quantify One Health Drivers of Antibiotic Resistance: A Preliminary Step towards Fostering ‘Antibiotic-Smart Communities’

The absence of objective criteria to measure the performance of ABR interventions in community settings makes it difficult to mobilize interest and investment for such interventions. The article presents a comprehensive list of indicators, developed from experiences gathered through community engagement work in Kerala, India and a consultative process with health, veterinary, environment, and development experts.

Formulating a Community-Centric Indicator Framework to Quantify One Health Drivers of Antibiotic Resistance: A Preliminary Step towards Fostering ‘Antibiotic-Smart Communities’ (January 2024). 

J Infect Public Health

Potential role of civil society organizations in antimicrobial resistance mitigation efforts in low- and middle-income countries: A report from India

Civil society organizations (CSOs) have been successful in complementing the efforts of government health systems, shaping various public health programs, especially in low- and middle-income countries. This article reports the outcomes of a CSO workshop held by one of the regional nodes of ReAct.

Potential role of civil society organizations (CSOs) in antimicrobial resistance (AMR) mitigation efforts in low- and middle-income countries: A report from India (December 2023). 

Research Square

Focus areas for the forward momentum of sub-national action plans on antimicrobial resistance (AMR) - Perspectives from three states in a Low- and middle-income Country

This article examines the factors and focus areas needed to formulate state-action plans (SAPs), in Low- and middle-income countries. Furthermore it reports the perspectives of key One Health stakeholders’ from three states in India.

Focus areas for the forward momentum of sub-national action plans on antimicrobial resistance (AMR) – Perspectives from three states in a Low- and middle-income Country (December 2023).

The Lancet Reg Health

Community engagement to mitigate antimicrobial resistance in low-and middle-income countries – an essential strategy for implementation of national action plans on AMR

The project was a four-year exercise to develop a model for community engagement. This model aimed to understand the perceptions around AMR in various community stakeholder groups and develop a set of interventions to contain the impact of AMR, in partnership with the community itself. This was done in Mallappuzhaserry, Kerala, India.

Community engagement to mitigate antimicrobial resistance in low-and middle-income countries – an essential strategy for implementation of national action plans on AMR (May 2024).

J Law Med & Ethics

Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response

In an article published in the latest Symposium Issue of the Journal of Law, Medicine & Ethics “Antimicrobial Resistance Must Be Included in the Pandemic Instrument to Ensure Future Global Pandemic Readiness”, ReAct calls for securing equitable and sustainable access to effective antibiotics and other countermeasures to be a key consideration in the upcoming pandemic instrument. See ReActs news about the publication here.

Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response (March 2023).

The Lancet

Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

The article argues why the proposed transferable exclusivity voucher (TEV), which has been suggested by the European Commission as a potential new incentive to be introduced in the revision of the EUs pharmaceutical legislation to stimulate antibiotic innovation should be abandoned. See ReActs update on the publication here.

Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation (January 2024).

 

The Lancet Global Health

An analysis of existing national action plans for antimicrobial resistance - gaps and opportunities in strategies optimising antibiotic use in human populations

This article presents a global assessment of national action plans on antimicrobial resistance in human health, revealing major gaps in policy, prescribing systems, technology, behaviours, delivery, and public engagement. These gaps highlight opportunities to facilitate the sustainable delivery and implementation of NAPs worldwide.

An analysis of existing national action plans for antimicrobial resistance – gaps and opportunities in strategies optimising antibiotic use in human populations (March 2023).

UNEP Report

Bracing for Superbugs: Strengthening environmental action in the One Health response to antimicrobial resistance

The United Nations Environment Programme (UNEP) recently released a new report on the environmental dimensions of antimicrobial resistance (AMR) highlighting how the misuse and overuse of antibiotics in humans, animals, and agriculture can contribute to the spread of drug-resistant infections. This, in turn, can cause severe consequences for public health, food security, and ecosystems. See ReActs discussion regarding the Report here.

Anthony So, Director of the ReAct Strategic Policy Program and the IDEA (Innovation + Design Enabling Access) Initiative at Johns Hopkins Bloomberg School of Public Health, is one of five lead authors of the report.

Bracing for Superbugs: Strengthening environmental action in the One Health response to antimicrobial resistance (February 2023).

The Lancet Global Health

An analysis of existing national action plans for antimicrobial resistance - gaps and opportunities in strategies optimising antibiotic use in human populations

The article examines the existing National Action Plans on Antimicrobial Resistance and identifies gaps and opportunities for improving strategies to optimize antibiotic use in human populations. Dr. Mirfin Mpundu, ReAct Africa, contributed to the article as one of the co-authors. See ReActs news about the publication here.

An analysis of existing national action plans for antimicrobial resistance – gaps and opportunities in strategies optimising antibiotic use in human populations (March 2023).

AMR Control Supplement

The Challenge for the Cancer Community

This Supplement to AMR Control is a collaboration between Global Health Dynamics and the Union for International Cancer Control (UICC) to provide the cancer community at all levels with up-to-date information and insights on the threat of antimicrobial resistance.

The growing antibiotic resistance (ABR) burden is a global public health issue that needs to be addressed urgently. The article considers the challenges faced by the cancer community, how antibiotics are used in cancer treatments and the impact of ABR on LMICs, and offers four key areas that need to be addressed by the cancer community in order to make progress against the threat of ABR.

The impact of antibiotic resistance on cancer treatment, especially in low-and middle-income countries, and the way forward – on page 46 in the report (2022).

The Lancet Global Health

Resetting the agenda for antibiotic resistance through a health systems perspective

This article discusses the gaps in how antibiotic resistance is currently addressed and suggests ways to improve the narrative. It shows how the COVID-19 pandemic highlighted both the urgent need to fight antibiotic resistance and the opportunity for stronger global cooperation.The need for capacity building and coordination at the national and global levels to strengthen the understanding of the importance of sustainable access to effective antibiotics for all health systems that could generate tangible links to current processes for global health and development.

Resetting the agenda for antibiotic resistance through a health systems perspective (July 2021).

Trends Ecol. Evol.

Coevolutionary Governance of Antibiotic and Pesticide Resistance

This article introduces the concept of coevolutionary governance to address antibiotic and pesticide resistance, outlining strategies to reduce biocide use, diversify practices, and strengthen collective action for sustainable solutions.

Coevolutionary Governance of Antibiotic and Pesticide Resistance (June 2020).

Int. J. Antimicrob. Agent

Comparison of antibiotic treatment guidelines for urinary tract infections in 15 European countries: Results of an online survey

This study compares national guidelines for urinary tract infections across Europe, revealing differences in treatment recommendations and highlighting the need for stronger research and coordinated antimicrobial resistance surveillance.

Comparison of antibiotic treatment guidelines for urinary tract infections in 15 European countries: Results of an online survey (October 2019).

Nature Sustainability

Antibiotic and pesticide susceptibility and the Anthropocene operating space

This Review discuss how rising antimicrobial and pesticide resistance threatens human health, agriculture, and ecosystems, introducing the “Anthropocene operating space” framework to assess the risks of declining biocide susceptibility.

Antibiotic and pesticide susceptibility and the Anthropocene operating space (November 2018).

Glob Public Health

Multidisciplinary and multisectoral coalitions as catalysts for action against antimicrobial resistance: Implementation experiences at national and regional levels

This article shares a five-step coalition-building approach, tested in Zambia, Ethiopia, Namibia, and regionally, to help stakeholders unite in tackling antimicrobial resistance (AMR).

Multidisciplinary and multisectoral coalitions as catalysts for action against antimicrobial resistance: Implementation experiences at national and regional levels (March 2018).

Lancet Infect Dis

Unavailability of old antibiotics threatens effective treatment for common bacterial infections

The article discusses the unavailability of old antibiotics and how is becoming a serious global problem. Despite remaining highly effective and preferred for many infections, these essential medicines face shortages, rising costs, and availability issues – threatening access to safe treatment for common bacterial infections.

Unavailability of old antibiotics threatens effective treatment for common bacterial infections (March 2018).

Int J Antimicrob Agents

Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia

This paper co-authored by ReAct and points out old but clinically useful antibiotics are not available in all countries. The situation regarding availability of these ‘forgotten antibiotics’ has worsened since 2011.

Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia (January 2017).

Nature

Use antimicrobials wisely

In this article, authors argue that UN must reframe action on antimicrobial resistance as the defence of a common resource. Better understanding can facilitate action on AMR from varying angles, namely infectious diseases, food security, natural resources and environmental conservation.

Use antimicrobials wisely (September 2016).

Int J Infect Dis

A Global Antimicrobial Conservation Fund for Low - and Middle - Income Countries

This paper co-authored by ReAct points out to the critical need to scale-up funding for low – and middle – income countries to support antimicrobial conservation and proposes a formation of the fund coordinating such support.

A Global Antimicrobial Conservation Fund for Low- and Middle-Income Countries (October 2016).

Ups J Med Sci

Antimicrobial resistance - a threat to the world's sustainable development

This paper examines how a number of the Sustainable Development Goals (SDGs) are impacted by antimicrobial resistance and suggests how to integrate the issue better into ongoing international policy processes using SDGs as an entry point.

Antimicrobial resistance-a threat to the world’s sustainable development (August 2016).

The lancet

UN High-Level Meeting on antimicrobials - what do we need?

In the light of culminating political attention to AMR at the 71st UN General Assembly, this paper highlights four key functions the ad hoc global coordinating mechanisms should bear, namely advocacy, monitoring and evaluation, resource mobilisation and coordination of multisectoral action.

UN High-Level Meeting on antimicrobials – what do we need? (July 2016).

PLoS Med

Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming a Promising Idea into Reality

The paper discusses different aspects of the delinkage model, the most promising incentive mechanism proposed to replace the current business model for antibiotics.

Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming Promising Idea into Reality (June 2016).

J Law Med Ethics

Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance

The world has a collective responsibility to preserve antibiotic effectiveness and access for all. This paper lays down policy implications and global governance tools necessary to addressed to resolve access vs. excess dilemma.

Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance (August 2015).

Bull World Health Organ

An international legal framework to address antimicrobial resistance

Authors propose a concept of a tripod – access, conservation, innovation – where all of these three areas need to be addressed simultaneously to maintain sustainability in global action. The paper also explores tools of an international law that can be utilised in assuring countries’ commitment to act.

An international legal framework to address antimicrobial resistance (February 2015).

The Lancet

International cooperation to improve access to and sustain effectiveness of antimicrobials

In this paper, authors elucidates interlinkages between access, conservation and innovation of antibiotics and the need to address these three elements simultaneously. Because of the multisectoral nature of the problem, having key global institutions and partners aligned under a One Health model is necessary.

International cooperation to improve access to and sustain effectiveness of antimicrobials (January 2016).

J Law Med Ethics

An Integrated Systems Approach is Needed to Ensure the Sustainability of Antibiotic Effectiveness for Both Humans and Animals

This paper identifies issues related to the use of antimicrobials in food-producing animals, provides examples of regional and country-level policies regulating non-therapeutic use of antibiotics and emphasises the need for a global coordination via international agreement to address these issues.

An Integrated Systems Approach is Needed to Ensure the Sustainability of Antibiotic Effectiveness for Both Humans and Animals (August 2015).

Ups J Med Sci

Overcoming scientific and structural bottlenecks in antibacterial discovery and development

Both financial and scientific bottlenecks hinder R&D of novel antibiotics. This paper delves deeper into the specifics of the different scientific and structural barriers, and offers some potential solutions.

Overcoming scientific and structural bottlenecks in antibacterial discovery and development (May 2014).

The Lancet Infec Diseases

Antibiotic resistance - the need for global solutions

This article series describes the global situation of antibiotic resistance, its major causes and consequences. Authors identify key areas spanning from epidemiology to global governance in which action is urgently needed.

Antibiotic resistance – the need for global solutions (December 2013).

BMJ

3Rs for innovating novel antibiotics: sharing resources, risks, and rewards

This article examines bottlenecks in the antibiotic pipeline. Authors argue that effective solutions are likely to include sharing the three Rs—resources, risks, and rewards along antibiotic development from discovery to post-marketing phases.

3Rs for innovating novel antibiotics: sharing resources, risks, and rewards (April 2012).